Supercharging Immune Cells May Help Control HIV Long-Term

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A Miracle cancer therapy that involves engineering a patient’s own immune cells is being repurposed for HIV, and early results from two individuals hint at its promise for long-term control of the virus.

As part of a clinical trial, scientists took people’s own immune cells and reprogrammed them in a lab to recognize and attack HIV in the body. After a single infusion of the modified cells, two individuals with HIV now have undetectable levels of the virus—one for nearly two years and the other for almost a year. Both have been able to go off HIV medications entirely.

The two people are part of a small study to test the treatment’s safety and feasibility. The initial findings were announced last week at the of American Society of Gene and Cell Therapy annual meeting in Boston.

“These are early days. If we can provide the proof-of-concept that this approach is...

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