Moderna gets $50 million to develop mRNA Ebola vaccine against Bundibugyo
Raging outbreak
CEPI will also provide $3.2 million to the International AIDS Vaccine Initiative, which is developing a vaccine that uses the same technology as Merck’s approved Ebola vaccine, Ervebo, which targets the more common Zaire ebolavirus strain.
Last, the CEPI is committing $8.6 million to the University of Oxford and Serum Institute of India, which is using its adenovirus-based vaccine platform, as it did for its COVID-19 vaccine during the pandemic.
There are two licensed vaccines against Ebola disease currently, including Ervebo and Zabdeno/Mvabea by Johnson & Johnson. Both vaccines target the Zaire strain, which has caused most of the large outbreaks to date, followed by the Sudan strain. The current outbreak is only the third driven by the Bundibugyo strain. As such, there are currently no licensed therapeutics or vaccines against it.
The lack of medical interventions is one of the challenges facing health officials responding to the...
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