Co-Scientist
Two of the biggest bottlenecks in aging research are deciding which genetic pathways to test and making sense of the vast data those experiments produce. Biologists Omar Abudayyeh and Jonathan Gootenberg are using Co-Scientist to help them blast through both.
Their lab runs huge genetic screens that flip thousands of genes on or off then reads how cells respond to these changes. The goal is to find changes that push cells away from senescence – a damaged state linked to aging – and toward a youthful state in tissues such as skin, hair, and muscle.
Co-Scientist is helping on two fronts. First, it generates leads. When the team asked it to trawl the scientific literature for factors that might reverse aging, it scanned tens of thousands of papers, considered a multitude of hypotheses, and ultimately proposed more than 20 novel, plausible genetic factors to test. Lab tests validated a couple...
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