Claude Designed 211 Proteins in Two Days. The Memes-in-Slack Phase Took Two Months

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Citrini Research has no lab, no biologists, and no drug discovery experience. It flew to Anthropic's New York office, ran an unreleased Claude against five scorpion toxins, and paid the wet lab on a credit card.

The number everyone is quoting from Anthropic's scorpion antivenom post is 318,484 — the count of protein designs an internal Claude model generated in 64 hours before narrowing to 180 for lab testing. It's the wrong number to fixate on.

The interesting numbers are 5 and 40. Five is the size of the team that commissioned the work: Citrini Research, a thematic equity research shop that sells investment notes, not medicines. Forty is roughly how many days it took to turn the designs into physical molecules and get data back.

A stock research firm walked into a frontier lab

Anthropic's framing is that it wanted to test whether motivated nonexperts could take a...

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